body.page-hereditary {
  line-height: 1;
}

#block-understandinghereditarytransthyretinamyloidosis {
  width: 100%;
  max-width: 955px;
  padding: 30px 20px;
  margin: 0 auto;
  text-align: center;
}

#block-understandinghereditarytransthyretinamyloidosis h2 {
  color: #ea5329;
  font-family: "Example Bold Old W00 Regular", "Helvetica Neue LT W05_75 Bold";
  text-transform: uppercase;
  font-size: 40px;
  line-height: 45px;
  letter-spacing: 0.08em;
  margin-bottom: 25px;
}

#block-understandinghereditarytransthyretinamyloidosis h3 {
  font-family: "Helvetica Neue LT W05_77 Bd Cn";
  font-weight: 500;
  color: #ea5329;
  font-size: 25px;
  margin-bottom: 25px;
  letter-spacing: 0.1em;
}

#block-understandinghereditarytransthyretinamyloidosis p {
  font-size: 15px;
  font-family: open-sans, sans-serif;
  color: #000;
  letter-spacing: 0.07em;
  line-height: 22px;
  margin-bottom: 20px;
  text-align: left;
}

#block-understandinghereditarytransthyretinamyloidosis p:last-child,
#block-hereditaryoverviewsection4 p:last-child {
  font-size: 12px;
  line-height: 16px;
}

#block-hereditaryoverviewsection4 {
  background: #000;
  padding: 50px 20px;
  margin: 50px 0;
  position: relative;
}

#block-clinicalcharacteristics {
  background: #000;
  padding-top: 15px;
  margin: 50px 0;
  position: relative;
}

#block-clinicalcharacteristics:before {
  content: "";
  width: 100%;
  height: 50px;
  position: absolute;
  top: -49px;
  left: 0;
  background: url(../images/bg-mid-up.png) repeat-x;
}

#block-clinicalcharacteristics:after {
  content: "";
  width: 100%;
  height: 50px;
  position: absolute;
  bottom: -49px;
  left: 0;
  background: url(../images/bg-mid-down.png) repeat-x;
}

.hereditary-overview.mid-column-section>div {
  padding-bottom: 0;
  max-width: 915px;
  width: 100%;
  background: #000;
  margin: 0 auto;
}

#block-hereditaryoverviewsection4 .overview-section {
  max-width: 915px;
  width: 100%;
  background: #000;
  margin: 0 auto;
}

#block-lifeexpectancy:before,
#block-hereditaryoverviewsection4:before {
  content: "";
  width: 100%;
  height: 50px;
  position: absolute;
  top: -49px;
  left: 0;
  background: url(../images/bg-mid-up.png) repeat-x;
}

#block-lifeexpectancy:after,
#block-hereditaryoverviewsection4:after {
  content: "";
  width: 100%;
  height: 50px;
  position: absolute;
  bottom: -49px;
  left: 0;
  background: url(../images/bg-mid-down.png) repeat-x;
}

#block-clinicalcharacteristics h2 {
  max-width: 960px;
  padding: 50px 20px 0px 20px;
  margin: 0 auto 40px;
  text-align: center;
  font-size: 35px;
  line-height: 40px;
  letter-spacing: 0.08em;
  color: #fff;
  font-family: "Helvetica Neue LT W05_47 Lt Cn";
  text-transform: inherit;
  text-transform: uppercase;
}

#block-clinicalcharacteristics div {
  width: 100%;
  max-width: 955px;
  padding: 0px 20px 50px 20px;
  margin: 0 auto;
}

#block-clinicalcharacteristics p,
#block-hereditaryoverviewsection4 p {
  font-size: 15px;
  font-family: open-sans, sans-serif;
  line-height: 22px;
  margin-bottom: 15px;
  color: #fff;
  list-style: disc;
  letter-spacing: 0.07em;
}

#block-clinicalcharacteristics ul {
  margin-bottom: 15px;
  padding-left: 32px;
}

#block-clinicalcharacteristics ul li {
  color: #fff;
  list-style: disc;
  font-family: open-sans, sans-serif;
  letter-spacing: 0.07em;
  font-size: 15px;
  line-height: 22px;
}

#block-clinicalcharacteristics p:last-child,
#block-lifeexpectancy p:last-child {
  width: 84%;
  border-left: 5px solid #e95427;
  margin: 0 auto;
  text-align: center;
  border-right: 5px solid #e95427;
  margin-top: 40px;
  font-family: "Helvetica Neue LT W05_47 Lt Cn";
  color: #fff;
  letter-spacing: 0.08em;
  text-align: center;
  text-transform: inherit;
  font-size: 20px;
  padding: 0 25px 0;
  line-height: 27.5px;
}

#block-clinicalcharacteristics div span,
.hereditary-overview.mid-column-section div h2 {
  display: block;
  color: #e95427;
  font-size: 25px;
  line-height: 35px;
  letter-spacing: 0.14em;
  font-family: "Helvetica Neue LT W05_77 Bd Cn";
  margin: 0 auto 40px;
  text-align: center;
  font-weight: 400;
}

.genotype-body h2 {
  padding: 0 20px;
  margin: 0 auto 40px;
  text-align: center;
  font-size: 35px;
  line-height: 40px;
  letter-spacing: .08em;
  color: #000;
  font-family: "Helvetica Neue LT W05_47 Lt Cn";
  text-transform: none;
  font-weight: 400;
}

.genotype-body p {
  text-align: left;
}

.genotype-phenotype p {
  font-size: 15px;
  line-height: 22px;
  font-family: open-sans, sans-serif;
  color: #000;
  letter-spacing: .07em;
}

.genotype-phenotype .main-container {
  position: relative;
}

.genotype-container {
  margin: 22px auto;
  border: 2px solid #faa41c;
}

.genotype-container .row-1 {
  display: grid;
  grid-template-columns: 45% 22% 7% 7% 5% 6%;
  padding: 10px 10px;
  align-items: center;
  grid-column-gap: 14px;
}

.genotype-container .row-2 {
  display: grid;
  grid-template-columns: 1fr 1fr 1fr;
  background: linear-gradient(to right, #faa41c, #e95328);
  color: #fff;
  padding: 2px 5px;
}

.genotype-container .row-1 .grid-item:nth-child(1),
.genotype-container .row-1 .grid-item:nth-child(2) {
  display: grid;
  grid-template-columns: 100%;
}

/* .genotype-container .grid-item {
    height: 37px;
} */
.genotype-container .grid-item {
  position: relative;
  cursor: pointer;
  width: 85px;
  padding: 2px;
}

.genotype-phenotype {
  width: 100%;
  max-width: 955px;
  padding: 50px 20px;
  margin: 0 auto;
  text-align: center;
}

.grid-item.one-col {
  width: min-content;
  padding: 8px 2px;
}

.grid-item span {
  width: auto;
  font-family: open-sans, sans-serif;
}

.grid-item span:first-of-type {
  font-family: "Example W00 Bold Italic", "Helvetica Neue LT W05_76 Bd It";
  font-size: 20px;
}

.grid-item span {
  width: auto;
  font-family: open-sans, sans-serif;
  line-height: 18px;
}

.sub-text {
  font-size: 12px;
  font-family: open-sans, sans-serif;
}

.genotype-container .row-2 div:nth-child(2n+1) {
  font-size: 21px;
}

.genotype-container .row-2 div:first-child {
  text-align: left;
}

.genotype-container .row-2 div:last-child {
  text-align: right;
}

.grid-item:hover {
  background: #e95328;
  color: #fff;
}

.grid-item .tooltip {
  visibility: hidden;
  position: absolute;
  font-size: 12px;
  top: -335%;
  left: -45px;
  width: 500px;
  border-top: 2px solid #e95328;
  border-bottom: 2px solid #e95328;
  border-left: 1px solid #e95328;
  border-right: 1px solid #e95328;
  background: #dbd4b7;
}

.genotype-container .row-1 .grid-item:nth-of-type(2) .tooltip {
  left: -214px;
}

.grid-item.one-col .tooltip {
  left: -384px;
}

.grid-item:hover .tooltip {
  visibility: visible;
  color: #000;
}

.t-head {
  display: grid;
  grid-template-columns: 1fr 1fr 1fr;
}

.grid-item .tooltip .t-head {
  background: #e95328;
}

.tooltip .t-head,
.tooltip .t-desc {
  display: grid;
  grid-template-columns: 1fr 1fr 1fr;
  grid-auto-rows: 40px 48px;
}

.tooltip .t-head>div:nth-child(2n+1) {
  font-family: "Helvetica Neue LT W05_47 Lt Cn";
  font-weight: bold;
  padding: 0 7px;
  margin: 5px 0;
}

.t-head div:nth-child(2n) {
  background: url(../images/table-background.png);
  line-height: normal;
}

.t-head div:nth-child(4) {
  grid-column: 2;
  grid-row: 2;
}

.t-head div:nth-child(2) {
  grid-column: 1;
  grid-row: 2;
}

.tooltip .t-head div:nth-child(2n) {
  text-align: left;
}

.tooltip .t-head div:nth-child(2n) {
  border: 1px solid red;
  border-bottom: none;
}

.tooltip .t-head div {
  padding: 7px;
  font-size: 14px;
}

.tooltip .t-head>div:nth-child(2n+1) {
  font-family: "Helvetica Neue LT W05_47 Lt Cn";
  font-weight: bold;
  padding: 0 7px;
  margin: 5px 0;
}

.tooltip .t-head div:nth-child(2n+1) {
  color: #fff;
  text-transform: uppercase;
  text-align: left;
}

.t-head div:nth-child(2n+1) {
  background: #e95328;
  line-height: 14px;
}

.tooltip .t-head div:nth-child(2n) {
  font-family: open-sans, sans-serif;
  font-size: 13px;
}

.tooltip .t-head div:nth-child(3),
.tooltip .t-head div:nth-child(4),
.tooltip .t-head div:nth-child(5),
.tooltip .t-head div:nth-child(6) {
  text-align: center;
}

.genotype-container .row-2 div:nth-child(2) {
  align-self: end;
}

.genotype-container .row-2 div {
  text-transform: uppercase;
}

.genotype-phenotype .hc-sub-content p {
  font-size: 12px;
  text-align: left;
}

.overview-section {
  padding: 20px 13px 10px;
}

.overview-section {
  border: 3px solid #e95427;
  width: 100%;
}

.overview-section>div:nth-child(1) {
  width: 25%;
}

.overview-section>div {
  color: white;
  display: inline-block;
  vertical-align: top;
  min-height: 205px;
}

.overview-section>div:nth-child(2) {
  width: 40%;
  display: inline-flex;
}

.overview-section>div:nth-child(3) {
  width: 33%;
}

.overview-section h4 {
  display: block;
  color: #e95427;
  text-transform: uppercase;
  font-family: "Helvetica Neue LT W05_77 Bd Cn";
  font-size: 18px;
  line-height: 25px;
  text-decoration: none;
  letter-spacing: 0.08em;
  font-weight: 400;
}

.overview-section ul {
  color: white;
  padding-left: 20px;
}

.overview-section li {
  color: white;
  list-style: disc;
  font-size: 15px;
  line-height: 22px;
  font-family: open-sans, sans-serif;
  letter-spacing: 0.07em;
}

.overview-section div.image {
  width: 30%;
}

.overview-section div.image>div {
  display: inline-block;
  vertical-align: top;
}

.overview-section div.image img {
  max-width: 90%;
  height: auto;
}

.overview-section div.image+div {
  width: 68%;
}

.overview-section>div:nth-child(2) h4 {
  color: white;
}

.overview-section div.image img {
  max-width: 90%;
  height: auto;
}

#block-hereditarysection5 {
  padding: 50px 0;
}

#block-hereditarysection5 .wrapper {
  max-width: 980px;
  margin: 0 auto;
  padding: 0 20px;
}

#block-hereditarysection5 .wrapper>h3 {
  margin-top: 10px;
  margin-bottom: 45px;
  text-align: center;
  letter-spacing: 0.08em;
  color: #000;
  font-family: "Helvetica Neue LT W05_77 Bd Cn";
  font-size: 25px;
  line-height: 35px;
}

#block-hereditarysection5 .wrapper .symptoms .graphic-image {
  padding-right: 10%;
}

#block-hereditarysection5 .wrapper .symptoms .symptoms-desc {
  width: 240px;
  min-width: 240px;
  padding: 0 10px;
  text-align: left;
}

#block-hereditarysection5 .wrapper .symptoms .graphic-image>img {
  margin: 0 0 0 auto;
  display: block;
  height: auto;
}

#block-hereditarysection5 .wrapper .symptoms .graphic-image .mobile {
  display: none;
  max-width: 350px;
  margin: 0 auto;
  text-align: center;
}

#block-hereditarysection5 .wrapper .symptoms .chart-footnote {
  margin-top: 60px;
  padding: 0 35px;
}

#block-hereditarysection5 .wrapper .symptoms .chart-footnote p {
  margin-bottom: 7px;
  text-align: left;
  letter-spacing: 0.07em;
  color: #000;
  font-family: open-sans, sans-serif;
  font-size: 12px;
  line-height: 16px;
}

#block-hereditarysection5 .wrapper .symptoms .symptoms-desc {
  width: 240px;
  min-width: 240px;
  padding: 0 10px;
  text-align: left;
}

#block-hereditarysection5 .wrapper .symptoms .symptoms-desc .highlight {
  margin: 0 -10px 20px;
  padding: 5px 10px;
  background: #e95427;
}

#block-hereditarysection5 .wrapper .symptoms .symptoms-desc .highlight>ul {
  padding-left: 14px;
  list-style: disc;
}

#block-hereditarysection5 .wrapper .symptoms .symptoms-desc .highlight>p {
  margin-bottom: 5px;
  letter-spacing: 0.1em;
  text-transform: uppercase;
  color: #fff;
  font-family: "Example W00 Bold Italic", "Helvetica Neue LT W05_76 Bd It";
  font-size: 18px;
  line-height: 25px;
}

.page-about .layout:nth-child(4) .wrapper .symptoms .symptoms-desc>ul li,
#block-hereditarysection5 .wrapper .symptoms .symptoms-desc>ul li {
  letter-spacing: 0.1em;
  color: #000;
  font-family: open-sans, sans-serif;
  font-size: 16px;
  line-height: 25px;
}

#block-hereditarysection5 .wrapper .symptoms .symptoms-desc>p {
  margin-bottom: 5px;
  letter-spacing: 0.1em;
  text-transform: uppercase;
  color: #201d0e;
  font-family: "Example W00 Bold Italic", "Helvetica Neue LT W05_76 Bd It";
  font-size: 18px;
  line-height: 25px;
}

#block-hereditarysection5 .wrapper .symptoms .symptoms-desc>ul {
  margin-bottom: 20px;
  padding-left: 14px;
  list-style: disc;
}

#block-hereditarysection5 .wrapper .symptoms .symptoms-desc .highlight>ul li {
  letter-spacing: 0.1em;
  color: #fff;
  font-family: open-sans, sans-serif;
  font-size: 16px;
  line-height: 25px;
}

#block-lifeexpectancy div {
  width: 100%;
  max-width: 955px;
  padding: 50px 20px;
  margin: 0 auto;
  color: #faa41d;
  font-family: "Helvetica Neue LT W05_47 Lt Cn";
  font-size: 20px;
  letter-spacing: 0.08em;
}

#block-lifeexpectancy h2 {
  max-width: 960px;
  padding: 0 20px;
  margin: 0 auto 40px;
  text-align: center;
  font-size: 35px;
  line-height: 40px;
  letter-spacing: 0.08em;
  color: #fff;
  font-family: "Helvetica Neue LT W05_47 Lt Cn";
  text-transform: inherit;
  font-weight: 100;
}

#block-lifeexpectancy p {
  font-size: 15px;
  font-family: open-sans, sans-serif;
  line-height: 22px;
  margin-bottom: 15px;
  color: #fff;
  list-style: disc;
  letter-spacing: 0.07em;
}

#block-lifeexpectancy h4 {
  width: 100%;
  border-left: 5px solid #e95427;
  padding: 0px 20px;
  margin: 0 auto;
  margin-top: 40px;
  text-align: center;
  border-right: 5px solid #e95427;
  font-family: "Helvetica Neue LT W05_47 Lt Cn";
  color: #faa41d;
  letter-spacing: 0.08em;
  text-align: center;
  text-transform: inherit;
  font-weight: normal;
}

#block-lifeexpectancy h4 {
  font-size: 24px;
  line-height: 29.5px;
}

#block-clinicalcharacteristics p:last-child,
#block-lifeexpectancy p:last-child {
  width: 84%;
  border-left: 5px solid #e95427;
  margin: 0 auto;
  text-align: center;
  border-right: 5px solid #e95427;
  margin-top: 40px;
  font-family: "Helvetica Neue LT W05_47 Lt Cn";
  color: #fff;
  letter-spacing: 0.08em;
  text-align: center;
  text-transform: inherit;
  font-size: 20px;
  padding: 0 25px 0;
  line-height: 27.5px;
}

#block-lifeexpectancy {
  background: #000;
  padding-top: 15px;
  margin: 50px 0;
  position: relative;
}

#block-lifeexpectancy p:last-child {
  margin: 0 auto;
}

#block-lifeexpectancy p:last-child {
  width: 100%;
  text-transform: unset;
}

#block-hereditarysection7 .inheritance-pattern.container {
  width: 100%;
  max-width: 955px;
  padding: 50px 20px;
  margin: 0 auto;
  text-align: center;
}

#block-hereditarysection7 h2 {
  padding: 0 20px;
  margin: 0 auto 40px;
  text-align: center;
  font-size: 35px;
  line-height: 40px;
  letter-spacing: 0.08em;
  color: #000;
  font-family: "Helvetica Neue LT W05_47 Lt Cn";
  text-transform: uppercase;
  font-weight: 400;
}

#block-hereditarysection7 p {
  text-align: left;
  font-size: 15px;
  line-height: 22px;
  font-family: open-sans, sans-serif;
  color: #000;
  letter-spacing: 0.07em;
}

#block-hereditarysection7 .image-container {
  margin: 40px 0px;
  display: flex;
  justify-content: space-between;
}

#block-hereditarysection7 .image-container>div {
  border: 3px solid #ea5229;
  padding: 20px 0;
  width: 48.854%;
}

#block-hereditarysection7 .image-container div h3 {
  color: #e95427;
  font-size: 17px;
  line-height: 22px;
  font-family: "Helvetica Neue LT W05_77 Bd Cn";
}

#block-hereditarysection7 .image-container .sec-img {
  display: flex;
  justify-content: space-between;
  padding: 15px 40px 0;
}

#block-hereditarysection7 .image-container .sec-img p span,
#block-hereditarysection7 .image-container>div:last-child>div:last-child>p span,
#block-hereditarysection7 .inheritance-pattern.container>div:first-child p span {
  font-family: "Helvetica Neue LT W01_56 It";
}

#block-hereditarysection7 .image-container .sec-img p span:first-child,
#block-hereditarysection7 .image-container>div:last-child>div:last-child>p span:first-child {
  font-family: "Helvetica Neue LT W05_75 Bold";
}

#block-hereditarysection7 .image-container .sec-img>div:first-child {
  width: 52.56%;
}

#block-hereditarysection7 .image-container .sec-img>div:nth-child(2) {
  width: 40%;
}

#block-hereditarysection7 .image-container .sec-img img {
  height: auto;
}

#block-hereditarysection7 p {
  text-align: left;
  font-size: 15px;
  line-height: 22px;
  font-family: open-sans, sans-serif;
  color: #000;
  letter-spacing: 0.07em;
}

#block-hereditarysection7 .inheritance-pattern.container {
  width: 100%;
  max-width: 955px;
  padding: 50px 20px;
  margin: 0 auto;
  text-align: center;
}

#block-hereditarysection7 .image-container p {
  font-size: 14px;
  line-height: 18px;
  letter-spacing: 0;
}

#block-hereditarysection7 .image-container .sec-img p {
  padding-top: 70%;
}

#block-hereditarysection7 .image-container>div:last-child>div:last-child>p {
  padding-top: 10px;
  margin: 30px 10px 0px;
  border-top: 2px solid grey;
}

#block-views-block-faq-listing-genetic-risk {
  background: #000;
  padding-top: 15px;
  margin: 50px 0 0;
  position: relative;
}



#block-views-block-faq-listing-genetic-risk::before {
  content: "";
  width: 100%;
  height: 50px;
  position: absolute;
  top: -49px;
  left: 0;
  background: url(../images/bg-mid-up.png) repeat-x;
}

#block-views-block-faq-listing-genetic-risk>div {
  max-width: 900px;
  width: 100%;
  background: #000;
  margin: 0 auto;
  padding: 40px 0 40px;
}



#block-views-block-faq-listing-genetic-risk h2 span {
  padding-top: 40px;
  text-transform: uppercase;
  display: inherit;
  width: 80%;
  color: #e95427;
  font-size: 25px;
  line-height: 35px;
  letter-spacing: 0.14em;
  font-family: "Helvetica Neue LT W05_77 Bd Cn";
  margin: 0 auto;
}

#block-views-block-faq-listing-genetic-risk p {
  position: relative;
  display: inline-block;
  margin-top: 10px;
  padding: 0 10px;
  vertical-align: middle;
  letter-spacing: 0.07em;
  border-left: 3px solid #ef4522;
  font-family: "Helvetica Neue LT W05_47 Lt Cn";
  font-size: 20px;
  font-weight: bold;
  line-height: 27.5px;
}

#block-views-block-faq-listing-genetic-risk p:after {
  position: absolute;
  top: 3px;
  right: -30px;
  width: 20px;
  height: 20px;
  content: "";
  background: url(../images/acc-close-plus.jpg) no-repeat transparent;
  background-size: 20px 20px;
}

#block-views-block-faq-listing-genetic-risk .views-field-field-title {
  cursor: pointer;
  padding: 0.5em 0;
}

#block-views-block-faq-listing-genetic-risk .views-field-field-title.active {
  padding-bottom: 0;
}

#block-views-block-faq-listing-genetic-risk .views-field-field-title.active p:after {
  background-image: url(../images/acc-open-minus.jpg);
}

#block-views-block-faq-listing-genetic-risk .views-field.views-field-body {
  margin-bottom: 20px;
}

#block-views-block-faq-listing-genetic-risk .views-field.views-field-body img {
  display: block;
  height: auto;
  width: 60%;
  margin: 50px auto;
}

#block-views-block-faq-listing-genetic-risk ul {
  margin: 10px 0 0;
  padding-left: 32px;
  list-style: disc;
}

#block-views-block-faq-listing-genetic-risk ul li {
  letter-spacing: 0.07em;
  font-family: open-sans, sans-serif;
  font-size: 15px;
  line-height: 22px;
}

#block-hereditarysection9 {
  color: #fff;
  background: #000;
  margin: 0 0 50px;
  padding-top: 65px;
  position: relative;
}

#block-hereditarysection9::after {
  content: "";
  width: 100%;
  height: 50px;
  position: absolute;
  bottom: -49px;
  left: 0;
  background: url(../images/bg-mid-down.png) repeat-x;
}

#block-hereditarysection9>div {
  padding: 0 20px 50px 20px;
  width: 100%;
  max-width: 955px;
  margin: 0 auto;
}

#block-hereditarysection9 h2 {
  width: 80%;
  display: block;
  color: #e95427;
  font-size: 25px;
  line-height: 35px;
  letter-spacing: .14em;
  font-family: "Helvetica Neue LT W05_77 Bd Cn";
  margin: 0 auto;
  max-width: 960px;
  padding: 0 20px;
  text-align: center;
  text-transform: inherit;
}

#block-hereditarysection9 table {
  border-collapse: collapse;
  border-spacing: 0;
  width: 100%;
  margin: 20px 0;
}

#block-hereditarysection9 table th,
#block-hereditarysection9 table td {
  border: 2px solid #faa51e;
  text-align: center;
  vertical-align: middle;
}

#block-hereditarysection9 table tr th {
  text-transform: uppercase;
  background: #e95427;
  padding: 10px 42px;
  text-transform: uppercase;
  font-family: "Helvetica Neue LT W05_47 Lt Cn";
  font-weight: bold;
  font-size: 18px;
  line-height: 22px;
  letter-spacing: .04em;
}

#block-hereditarysection9 table tr td {
  padding: 10px;
  font-family: open-sans, sans-serif;
}

#block-hereditarysection9 table span,
#block-hereditarysection9 h2 span {
  font-style: italic;
}

#block-hereditarysection9 p {
  font-size: 15px;
  line-height: 22px;
  font-family: open-sans, sans-serif;
  letter-spacing: .07em;
}

#block-frequencymonitoring {
  width: 100%;
  max-width: 955px;
  padding: 50px 20px;
  margin: 0 auto;
  text-align: center;
}

#block-frequencymonitoring div {
  display: flex;
  width: 100%;
  max-width: 960px;
  flex-wrap: wrap;
}

/* #block-understandinghereditarytransthyretinamyloidosis h2, 
#block-understandinghereditarytransthyretinamyloidosis p, 
#block-clinicalcharacteristics h2,
 #block-clinicalcharacteristics p:last-child, 
#block-lifeexpectancy p:last-child, 
#block-lifeexpectancy div, 
#block-lifeexpectancy h2, 
#block-lifeexpectancy h4, 
#block-frequencymonitoring div p, 
#block-frequencymonitoring h2, 
#block-hereditaryoverviewsection4 p, 
#block-resourcesfirst h1, .overview-section li {
    margin: 0;
    padding: 0;
    border: 0;
    font-size: 100%;
    font: inherit;
    vertical-align: baseline;
} */

#block-frequencymonitoring div p {
  padding: 30px;
  border: 3px solid #ea5229;
  align-content: center;
  position: relative;
  display: flex;
  /* align-items: center; */
  flex-direction: column;
  justify-content: center;
  margin: 0px 15px 15px 15px;
  max-width: 100%;
  width: calc(33.33% - 30px);
  font-size: 15px;
  line-height: 22px;
  font-family: open-sans, sans-serif;
  color: #000;
  letter-spacing: 0.07em;
}

#block-frequencymonitoring div p::before {
  content: " ";
  position: absolute;
  background: #ea5328;
  border-radius: 50px;
  line-height: 35px;
  color: #fff;
  font-weight: bold;
  font-size: 24px;
  box-sizing: border-box;
  width: 45px;
  height: 45px;
  top: 50%;
  left: -22.5px;
  transform: translateY(-50%);
  display: flex;
  align-items: center;
  justify-content: center;
}

#block-frequencymonitoring div p:nth-of-type(1)::before {
  content: "1";
}

#block-frequencymonitoring div p::after {
  content: "";
  background: #ea5328;
  position: absolute;
  width: 30px;
  height: 3px;
  top: 50%;
  left: -34px;
  transform: translateY(-50%);
}

#block-frequencymonitoring div p:nth-of-type(1)::after {
  height: 0;
  width: 0;
}

#block-frequencymonitoring div p:nth-of-type(2)::before {
  content: "2";
}

#block-frequencymonitoring div p:nth-of-type(3)::before {
  content: "3";
}

#block-frequencymonitoring div p span {
  display: contents;
}

#block-frequencymonitoring div h5 {
  padding: 10px 60px;
  font-weight: bold;
  font-family: "Helvetica Neue LT W05_77 Bd Cn";
  font-size: 18px;
  letter-spacing: 0;
  margin: 20px 13px;
  background: #faa41e;
}

#block-frequencymonitoring h2,
#block-views-block-faq-listing-genetic-risk h2 {
  width: 100%;
  max-width: 960px;
  padding: 0 20px;
  margin: 0 auto 40px;
  text-align: center;
  font-size: 35px;
  line-height: 40px;
  letter-spacing: 0.08em;
  color: #000;
  font-family: "Helvetica Neue LT W05_47 Lt Cn";
  text-transform: uppercase;
  font-weight: 400;
}

#block-views-block-faq-listing-genetic-risk h2,
#block-views-block-faq-listing-genetic-risk p,
#block-views-block-faq-listing-genetic-risk ul,
#block-views-block-faq-listing-genetic-risk ul li {
  color: #fff;
}

#block-hereditarysection11 {
  margin: 50px 0;
  background: #000;
  position: relative;
}

#block-hereditarysection11::before {
  position: absolute;
  top: -49px;
  left: 0;
  width: 100%;
  height: 50px;
  content: "";
  background: url(../images/bg-mid-up.png) repeat-x;
}

#block-hereditarysection11::after {
  position: absolute;
  bottom: -49px;
  left: 0;
  width: 100%;
  height: 50px;
  content: "";
  background: url(../images/bg-mid-down.png) repeat-x;
}

#block-hereditarysection11 .btn-cta {
  width: 100%;
  padding: 50px 0;
  text-align: center;
}

#block-hereditarysection11 .btn-cta a {
  position: relative;
  position: relative;
  z-index: 2;
  display: inline-block;
  min-width: 410px;
  padding: 13px 80px;
  -webkit-transition: all 0.5s ease;
  -moz-transition: all 0.5s ease;
  -ms-transition: all 0.5s ease;
  -o-transition: all 0.5s ease;
  transition: all 0.5s ease;
  vertical-align: top;
  text-decoration: none;
  border: 3px solid #faa51e;
}

#block-hereditarysection11 .btn-cta a:hover>span:nth-child(1) {
  color: #fff;
}

#block-hereditarysection11 .btn-cta a>span:nth-child(1) {
  display: block;
  letter-spacing: 0.1em;
  text-transform: uppercase;
  color: #faa51e;
  font-family: "Example W00 Bold Italic", "Helvetica Neue LT W05_76 Bd It";
  font-size: 18px;
  line-height: 24px;
}

#block-hereditarysection11 .btn-cta a>span:nth-child(2) p {
  display: block;
  letter-spacing: 0.08em;
  text-transform: uppercase;
  color: #fff;
  font-family: "Helvetica Neue LT W05_77 Bd Cn";
  font-size: 16px;
  line-height: 24px;
}

#block-hereditarysection11 .btn-cta a:after {
  position: absolute;
  top: 50%;
  right: 15px;
  width: 10px;
  height: 16px;
  content: "";
  -webkit-transition: all 0.5s ease;
  -moz-transition: all 0.5s ease;
  -ms-transition: all 0.5s ease;
  -o-transition: all 0.5s ease;
  transition: all 0.5s ease;
  -webkit-transform: translateY(-50%);
  -moz-transform: translateY(-50%);
  -ms-transform: translateY(-50%);
  -o-transform: translateY(-50%);
  transform: translateY(-50%);
  background: url(../images/next-arrow.png) no-repeat center center;
}

#block-hereditarysection11 .btn-cta a:before {
  position: absolute;
  z-index: -2;
  top: 0;
  right: 50%;
  bottom: auto;
  bottom: 0;
  left: 50%;
  height: 100%;
  content: "";
  -webkit-transition: all 0.5s ease;
  -moz-transition: all 0.5s ease;
  -ms-transition: all 0.5s ease;
  -o-transition: all 0.5s ease;
  transition: all 0.5s ease;
  opacity: 0;
  background-color: #faa51e;
}

#block-hereditarysection11 .btn-cta a:hover:before {
  right: 0;
  left: 0;
  opacity: 1;
}

#block-hereditarysection11 .btn-cta a:hover>span:nth-child(2) p {
  color: #000;
}

#block-hereditarysection11 .btn-cta a:hover:after {
  background: url(../images/next-arrow-hover.png) no-repeat center center;
}

@media screen and (min-width: 768px) {
  .genotype-container .row-2 div:nth-child(2) {
    letter-spacing: .15em;
  }

  .tooltip .t-head div:nth-child(4n+4) {
    line-height: 28px;
  }

  .genotype-container .grid-item {
    height: 37px;
  }

  .grid-item:hover::after {
    content: '';
    position: absolute;
    color: #e95328;
    top: -87%;
    left: 35%;
    font-size: 25px;
    width: 0;
    height: 0;
    border-left: 10px solid transparent;
    border-right: 10px solid transparent;
    border-top: 15px solid #e95328;
  }

  .genotype-container .row-2 div {
    font-family: Helvetica Neue LT W01_57 Cond;
    font-weight: 600;
    letter-spacing: 1px;
  }

  .genotype-container .row-2 div {
    font-family: Helvetica Neue LT W01_57 Cond;
    font-weight: 600;
    letter-spacing: 1px;
  }

  #block-hereditarysection5 .wrapper .symptoms {
    display: -webkit-box;
    display: -ms-flexbox;
    display: flex;
    -webkit-box-pack: justify;
    -ms-flex-pack: justify;
    justify-content: space-between;
  }

}

.genotype-container .row-2 div:nth-child(2) {
  align-self: end;
}

@media all and (-ms-high-contrast: none),
(-ms-high-contrast: active) {

  /* IE10+ CSS here */
  .genotype-container .row-1 {
    display: -ms-grid;
    display: grid;
    -ms-grid-columns: 45% 14px 22% 14px 7% 14px 7% 14px 5% 14px 6%;
    grid-template-columns: 45% 22% 7% 7% 5% 6%;
    padding: 10px 10px;
    -webkit-box-align: center;
    -ms-flex-align: center;
    align-items: center;
    grid-column-gap: 14px;
  }

  .genotype-container .row-1 .grid-item:nth-child(1),
  .genotype-container .row-1 .grid-item:nth-child(2) {
    display: -ms-grid;
    display: grid;
    -ms-grid-columns: 100%;
    grid-template-columns: 100%;
  }

  .tooltip .t-head,
  .tooltip .t-desc {
    display: -ms-grid;
    display: grid;
    -ms-grid-columns: 1fr 1fr 1fr;
    grid-template-columns: 1fr 1fr 1fr;
    grid-auto-rows: 40px 48px;
  }

  .row-1 .grid-item:first-child {
    -ms-grid-column: 1;
  }

  .row-1 .grid-item:nth-child(2) {
    -ms-grid-column: 2;
  }

  .row-1 .grid-item:nth-child(3) {
    -ms-grid-column: 4;
  }

  .row-1 .grid-item:nth-child(4) {
    -ms-grid-column: 6;
  }

  .row-1 .grid-item:nth-child(5) {
    -ms-grid-column: 8;
  }

  .row-1 .grid-item:nth-child(6) {
    -ms-grid-column: 10;
  }

  .genotype-container .row-2 {
    display: -ms-grid;
    display: grid;
    -ms-grid-columns: 1fr 1fr 1fr;
    grid-template-columns: 1fr 1fr 1fr;
  }

  .genotype-container .row-2 div:nth-child(2) {
    -ms-grid-column: 2;
  }

  .genotype-container .row-2 div:last-child {
    -ms-grid-column: 3;
  }

  .grid-item .tooltip .t-head div:first-child {
    -ms-grid-column: 1;
    -ms-grid-row: 1;
  }

  .grid-item .tooltip .t-head div:nth-child(2) {
    -ms-grid-column: 1;
    -ms-grid-row: 2;
  }

  .grid-item .tooltip .t-head div:nth-child(3) {
    -ms-grid-column: 2;
    -ms-grid-row: 1;
  }

  .grid-item .tooltip .t-head div:nth-child(4) {
    -ms-grid-column: 2;
    -ms-grid-row: 2;
  }

  .grid-item .tooltip .t-head div:nth-child(5) {
    -ms-grid-column: 3;
    -ms-grid-row: 1;
  }

  .grid-item .tooltip .t-head div:nth-child(6) {
    -ms-grid-column: 3;
    -ms-grid-row: 2;
  }

  .tooltip .t-head div:nth-child(2n + 1) {
    height: 40px;
  }

  .tooltip .t-head div:nth-child(2n) {
    height: 48px;
  }

  .box-count {
    display: -ms-grid;
    display: grid;
    -ms-grid-columns: 1fr 40px 1fr 40px 1fr;
    grid-template-columns: 1fr 1fr 1fr;
    grid-gap: 40px;
  }

  .box-count div.box-count-one {
    -ms-grid-column: 1;
    padding-top: 35%;
  }

  .box-count div.box-count-two {
    -ms-grid-column: 3;
  }

  .box-count div.box-count-three {
    -ms-grid-column: 5;
    padding-top: 23%;
  }

  .image-container>div {
    display: inline-block;
    vertical-align: top;
    width: 49%;
    height: 523px;
  }

  .image-container .sec-img {
    display: -ms-grid;
    -ms-grid-columns: 1.5fr 1fr;
    position: relative;
  }

  .image-container .sec-img p {
    position: absolute;
    top: -164px;
    width: 33%;
    right: 6%;
  }

  .image-container>div:nth-child(1) {
    margin-right: 13px;
  }

  .grid-item .tooltip {
    top: -361%;
  }

  .grid-item:last-child .tooltip .t-head div:last-child,
  .grid-item:nth-child(3) .tooltip .t-head div:last-child,
  .grid-item:first-child .tooltip .t-head div:last-child {
    line-height: 12px;
  }

  .genotype-container .row-1 {
    -ms-grid-columns: 45% 14px 22% 14px 7% 12px 7% 23px 5% 14px 6%;
  }

  .genotype-container .row-1 :nth-child(1).grid-item,
  .genotype-container .row-1 :nth-child(2).grid-item {
    line-height: 13px;
    padding-top: 5px;
  }

  .genotype-container .row-2 div:nth-child(2) {
    padding-top: 5px;
  }

  .generic-risk.mid-column-section h2 span.itl {
    display: inline-block;
  }

  .genotype-container .row-1 {
    grid-template-columns: 45% 22% 6% 6% 6% 0%;
  }

}

@media screen and (max-width: 955px) {
  #block-hereditarysection9 table tr th {
    padding: 5px;
  }

  #block-hereditarysection9 table tr td {
    padding: 10px 5px;
  }
}

@media screen and (min-width: 768px) and (max-width: 1000px) {
  .genotype-container .row-1 {
    grid-template-columns: 41% 18% 8% 8% 7% 8%;
    grid-column-gap: 2%;
  }

  .grid-item .tooltip {
    left: -10px;
  }

  .grid-item.one-col:last-child .tooltip {
    left: -430px;
  }

  .overview-section>div:nth-child(1),
  .overview-section>div:nth-child(2) {
    width: 49%;
  }

  .overview-section>div:nth-child(3) {
    width: 100%;
  }
}

/* Mobile responsive */

@media screen and (max-width: 767px) {
  #block-understandinghereditarytransthyretinamyloidosis h2 {
    color: #ea5329;
    text-transform: uppercase;
    margin: 25px auto;
    font-size: 25px;
    line-height: 30px;
    letter-spacing: 0.08em;
  }

  #block-understandinghereditarytransthyretinamyloidosis h3 {
    font-size: 22px;
    font-family: "Helvetica Neue LT W05_77 Bd Cn";
  }

  #block-clinicalcharacteristics h2 {
    padding: 10px 20px 0;
    font-weight: 100;
  }

  #block-clinicalcharacteristics ul {
    padding-left: 18px;
  }

  #block-clinicalcharacteristics>div>p:last-of-type {
    width: 90%;
    padding: 0 25px;
    border-left: 2px solid #e95427;
    border-right: 2px solid #e95427;
  }

  .hereditary-overview.mid-column-section div h2 {
    letter-spacing: 0.09em;
    margin-bottom: 15px;
  }

  .overview-section>div:nth-child(1) {
    width: 100%;
    border-bottom: 1px solid;
    min-height: 170px;
    margin-bottom: 25px;
  }

  .overview-section>div:nth-child(1),
  .overview-section>div:nth-child(2),
  .overview-section>div:nth-child(3) {
    width: 100%;
  }

  .overview-section div.image {
    margin: 40px 0 30px;
  }

  .overview-section>div:nth-child(2) h4 {
    margin-left: -43%;
  }

  .overview-section>div:nth-child(2) ul {
    margin: 10px 15px;
  }

  #block-hereditarysection5 .wrapper>h3 {
    margin: 10px auto 45px;
    font-size: 25px;
    line-height: 30px;
  }

  #block-hereditarysection5 .wrapper .symptoms .graphic-image {
    padding-right: 0;
  }

  #block-hereditarysection5 .wrapper .symptoms .graphic-image>img {
    margin: 0 auto;
    display: block;
  }

  .page-about .layout:nth-child(4) .wrapper .symptoms .symptoms-desc,
  #block-hereditarysection5 .wrapper .symptoms .symptoms-desc {
    width: 100%;
    margin-bottom: 25px;
  }

  #block-lifeexpectancy p:last-child,
  #block-lifeexpectancy h4 {
    width: 100%;
    padding: 0px 10px;
    border-left: 2px solid #e95427;
    border-right: 2px solid #e95427;
  }

  #block-hereditarysection9 {
    padding: 50px 0 10px;
  }

  #block-hereditarysection9>div {
    padding: 0 20px 30px 20px;
  }

  #block-hereditarysection9 h2 {
    font-size: 20px;
    width: 100%;
    line-height: 25px;
  }

  #block-hereditarysection9 table {
    margin: 30px 0;
  }

  #block-hereditarysection9 table tr th {
    padding: 5px;
    line-height: 1.2;
    font-size: 10px;
  }

  #block-hereditarysection9 table tr td {
    font-size: 10px;
    word-break: break-all;
    padding: 10px 5px;
  }

  #block-hereditarysection11 .btn-cta {
    max-width: 320px;
    padding: 0 14px;
    margin: 0 auto;
  }

  #block-views-block-faq-listing-genetic-risk>div {
    padding: 10px 15px 20px;
  }

  #block-views-block-faq-listing-genetic-risk h2 span {
    font-size: 20px;
    width: 100%;
    line-height: 25px;
  }

  #block-views-block-faq-listing-genetic-risk p {
    padding-right: 30px;
    margin-right: 25px;
    font-size: 18px;
    width: calc(100% - 25px);
  }

  #block-views-block-faq-listing-genetic-risk .views-field.views-field-body img {
    width: 90%;
    margin: 10px auto 0;
  }

  #block-frequencymonitoring {
    padding: 20px 20px;
  }

  #block-frequencymonitoring h2 {
    margin: 0 auto 50px;
    font-size: 28px;
  }

  #block-frequencymonitoring div p {
    height: 325px;
    margin: 0 0 40px;
    width: 100%;
    padding: 30px 60px;
  }

  #block-frequencymonitoring div p::before {
    top: -2px;
    left: 50%;
    transform: translate(-50%, -50%);
  }

  #block-frequencymonitoring div p::after {
    width: 3px;
    height: 27px;
    top: -30px;
    left: 50%;
    transform: translate(-50%, -50%);
  }

  #block-frequencymonitoring div p:nth-of-type(3) {
    margin-bottom: 0;
  }

  #block-frequencymonitoring div h5 {
    padding: 10px 15px;
    font-weight: bold;
    font-size: 12px;
    line-height: 1.5em;
  }

  #block-hereditarysection11 .btn-cta {
    max-width: 320px;
    padding: 0 14px;
    margin: 0 auto;
  }

  #block-hereditarysection11 .btn-cta a {
    width: 100%;
    min-width: 0;
    padding: 15px 40px;
  }

  #block-hereditarysection7 .inheritance-pattern.container {
    padding: 20px 20px;
  }

  #block-hereditarysection7 .inheritance-pattern.container h2 {
    margin: 0 auto 20px;
    font-size: 28px;
  }

  #block-hereditarysection7 p,
  #block-hereditarysection7 .image-container p {
    font-size: 15px;
  }

  #block-hereditarysection7 .image-container p {
    line-height: 22px;
    letter-spacing: 0.07em;
  }

  #block-hereditarysection5 .wrapper .symptoms .chart-footnote {
    margin: 35px 0;
    padding: 0;
  }

  #block-hereditarysection7 .image-container>div:last-child>div:last-child>p {
    margin: 30px 0 0;
  }

  #block-hereditarysection7 .image-container {
    flex-wrap: wrap;
  }

  #block-hereditarysection7 .image-container>div {
    width: 100%;
    padding: 10px 20px;
  }

  #block-hereditarysection7 .image-container>div+div {
    margin-top: 20px;
  }

  #block-hereditarysection7 .image-container .sec-img {
    margin-top: 10px;
    padding: 0;
  }

  #block-hereditarysection7 .image-container .sec-img p {
    padding-top: 0;
  }

  #block-hereditarysection7 .image-container .sec-img>div:first-child {
    width: 56.9%;
  }

  #block-hereditarysection7 .image-container .sec-img>div:nth-child(2) {
    width: 38%;
  }

  .br-desk {
    display: none;
  }

  .genotype-phenotype {
    padding: 20px 20px;
  }

  .genotype-body h2 {
    margin: 0 auto 20px;
    font-size: 28px;
  }

  .genotype-container {
    display: grid;
    grid-template-columns: 34px 98px auto;
    border: none;
  }

  .genotype-container .row-1 {
    display: grid;
    grid-template-columns: 1fr;
    padding: 10px 10px;
    align-items: baseline;
    grid-column-gap: 14px;
    grid-column: 2;
    grid-row: 1/3;
    grid-template-rows: 47% 12% 11% 10% 10% 10%;
    border-image-outset: 0;
    border-image-repeat: stretch;
    border-image-slice: 100%;
    border-image-source: none;
    border-image-width: 1;
    border-width: 4px;
    border-style: solid;
    border-image: linear-gradient(to bottom, #faa41c, #e95328);
    border-image-slice: 100%;
    border-image-slice: 1;
  }

  .genotype-container .row-2 {
    display: grid;
    grid-template-columns: unset;
    grid-column: 1;
    grid-row: 1/3;
    grid-gap: 23px;
    padding-right: 7px;
    background: linear-gradient(to bottom, #faa41c, #e95328);
  }

  .genotype-container .grid-item {
    position: unset;
    margin: 0 auto;
  }

  .genotype-container .row-1 .grid-item:nth-child(1),
  .genotype-container .row-1 .grid-item:nth-child(2) {
    display: unset;
    grid-template-columns: unset;
  }

  .grid-item .tooltip {
    top: 0;
    left: 140px;
    width: calc(100% - 140px);
    background: none;
  }

  .tooltip .t-head,
  .tooltip .t-desc {
    grid-template-columns: 1fr;
    grid-auto-rows: 19px 106px;
  }

  .grid-item .tooltip .t-head {
    background: none;
    border: 3px solid #e95328;
  }

  .tooltip .t-head div {
    font-size: 16px;
  }

  .tooltip .t-head>div {
    align-self: center;
    border: unset;
    background: none;
  }

  .tooltip .t-head>div:nth-child(2n+1) {
    margin: 0;
    font-family: Helvetica Neue LT W01_77 Bd Cn;
    text-transform: unset;
    padding: 4px 0;
    font-size: 18px;
    background: #e95328;
    text-align: center;
  }

  .tooltip .t-head div:nth-child(2n) {
    font-size: 16px;
    padding: 5px 2px;
    text-align: center;
    border: none;
  }

  .genotype-container .row-1 .grid-item:nth-of-type(2) .tooltip,
  .grid-item.one-col:hover .tooltip {
    left: 140px;
  }

  .tooltip .t-head div:nth-child(4) {
    grid-column: unset;
    grid-row: unset;
  }

  .genotype-container .row-2 div {
    writing-mode: vertical-rl;
    text-orientation: mixed;
    font-size: 14px;
    font-family: open-sans, sans-serif;
    text-transform: unset;
  }

  .genotype-container .row-2 div:nth-child(2) {
    font-family: Helvetica Neue LT W01_77 Bd Cn;
    font-size: 21px;
  }

  .genotype-phenotype p.hc-sub-content,
  .hereditary-content p.hc-sub-content {
    line-height: 16px;
  }

  .grid-item:hover::after {
    content: '';
    position: absolute;
    color: #e95328;
    font-size: 20px;
    left: 115px;
    width: 0;
    height: 0;
    border-top: 8px solid transparent;
    border-bottom: 8px solid transparent;
    border-right: 28px solid #e95328;
  }

  .genotype-container .row-1 .grid-item:nth-child(1)::after {
    top: 23px;
  }

  .genotype-container .row-1 .grid-item:nth-child(2)::after {
    top: 50%;
  }

}

@media screen and (max-width: 320px) {
  .tooltip .t-head>div:nth-child(2n+1) {
    font-size: 16px;
  }

  .genotype-container .row-1 {
    padding: 2px;
  }

  .genotype-container {
    grid-template-columns: 28px 82px auto;
  }

  .grid-item .tooltip,
  .genotype-container .row-1 .grid-item:nth-of-type(2) .tooltip,
  .grid-item.one-col:hover .tooltip {
    left: 115px;
    width: calc(100% - 115px);
  }

  .grid-item:hover::after {
    left: 102px;
    border-top: 6px solid transparent;
    border-bottom: 6px solid transparent;
    border-right: 17px solid #e95328;
  }

  #block-frequencymonitoring div p {
    padding: 30px 60px;
  }
}